Overlap Layout Consensus (De Novo Genome Assembly De Novo Genome Assembly)

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Time Complexity

$O(n^{2})$

Space Complexity

$O(n^{2})$? words

(Computes and stores all acceptable overlaps among all fragment pairs, along with detailed information regarding alignment, during one of the steps. Overlap graph has size at most O(n^2), layout and consensus should not take up more than O(n^2) space)

Description

Approximate?

Approximate

Approximation Factor:

Randomized?

No, deterministic

Model of Computation

Word RAM

Year

1987

Reference